The Journal of Organic Chemistry

Resolution of trifluoromethylcarbinols

DM Feigl, HS Mosher

Index: Feigl,D.M.; Mosher,H.S. Journal of Organic Chemistry, 1968 , vol. 33, # 11 p. 4242 - 4245

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Citation Number: 18

Abstract

When an enantiomerically pure reagentlo (R 111) is allowed to react with a carbinol (I) consisting of a mixture of enantiomers, a mixture of epimers (R, R IV and X, R IV) will result. If there is no racemization of carbinol (I), reagent (111), or products (IV), and if there is no kinetic resolution during this process, then the mixture of epimers (R, R IV and S, R IV) will be formed in exactly the same ratio as the enantiomers initially present. Therefore, any ...

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