Tetrahedron letters

Ring closing metathesis reactions on a phosphonate template

PR Hanson, DS Stoianova

Index: Hanson, Paul R.; Stoianova, Diana S. Tetrahedron Letters, 1998 , vol. 39, # 23 p. 3939 - 3942

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Citation Number: 61

Abstract

The first examples of ring-closing metathesis reactions on a phosphonate template catalyzed by the ruthenium alkylidene 3 are described. The yield, rate, and mode of cyclization in these reactions are sensitive to simple olefin substitution. The highlight of this method is the efficient syntheses of 2-alkyloxy-3, 6-dihydro-[1, 2] oxaphosphinine 2-oxide heterocycles (2).