Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8??Selective Inhibitors

T Suzuki, N Muto, M Bando, Y Itoh, A Masaki…

Index: ChemMedChem, , vol. 9, # 3 p. 657 - 664

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Abstract

... ChemMedChem, 9: 657–664. ... Volume: Issue: Page ... 3-[2-(phenylthiomethyl)thiazol-4-yl]-N- hydroxybenzamide (9): Compound 9 (48 % yield) was prepared from compound 26 according to the procedure for the preparation of compound 8: mp: 56–60 °C; 1 H NMR (500 MHz, CD 3 ...

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Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8??Selective Inhibitors

[Suzuki, Takayoshi; Muto, Nobusuke; Bando, Masashige; Itoh, Yukihiro; Masaki, Ayako; Ri, Masaki; Ota, Yosuke; Nakagawa, Hidehiko; Iida, Shinsuke; Shirahige, Katsuhiko; Miyata, Naoki ChemMedChem, 2014 , vol. 9, # 3 p. 657 - 664]

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