5-Chloroindole 계화합물의Large Scale 합성
…, S Palle, V Ramanatham, M Khagga…
Index: Keetha, Laxminarayana; Palle, Sadanandam; Ramanatham, Vinodkumar; Khagga, Mukkanti; Chinnapillai, Rajendiran Journal of the Korean Chemical Society, 2011 , vol. 55, # 2 p. 240 - 242
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Abstract
ABSTRACT. A large scale and commercially feasible synthesis of 5-chloroindole and its 3- substituted analogues has been described via a halogen-halogen exchange reaction from 5- bromoindole and its derivatives using cuprous chloride and dipolar aprotic solvent N-methyl- 2-pyrrolidone in one pot with good yields. Keywords: 5-haloindoles, copper (I) chloride, N- methyl-2-pyrrolidone, halogen-halogen exchange.
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