An improved synthesis of memantine hydrochloride: anti-Alzheimer's drug

JM Reddy, G Prasad, V Raju…

Index: Organic Process Research and Development, , vol. 11, # 2 p. 268 - 269

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Citation Number: 4

Abstract

... An economical new process route has been developed for the large-scale synthesis of ... by salt formation produces the memantine hydrochloride 1 (Scheme 1). 4 This procedure results in ... by washing with 15% sodium bisulphate solution (4.0 L); the separated organic layer was ...