Cu (OTf) 2-catalyzed synthesis of imidazo [1, 2-a] pyridines from α-diazoketones and 2-aminopyridines

…, BVS Reddy, YG Rao, M Srinivas, AV Narsaiah

Index: Yadav; Subba Reddy; Gopal Rao; Srinivas; Narsaiah Tetrahedron Letters, 2007 , vol. 48, # 43 p. 7717 - 7720

Full Text: HTML

Citation Number: 67

Abstract

α-Diazoketones undergo smooth coupling with 2-aminopyridines in the presence of 10mol% of copper (II) triflate to produce the corresponding 2-substituted imidazo [1, 2-a] pyridines (IPs) in excellent yields with high selectivity. Rh2 (OAc) 4 is also found to be an equally effective catalyst for this transformation.

Related Articles:

Facile three-component domino reactions for the synthesis of 2-arylimidazo [1, 2-a] pyridines and 2-arylimidazo [2, 1-a] isoquinolines

[Prasanna, Pitchaimani; Kumar, Sundaravel Vivek; Gunasekaran, Pethaiah; Perumal, Subbu Tetrahedron Letters, 2013 , vol. 54, # 29 p. 3740 - 3743]

Silver??Catalyzed Cyclization of N??(Prop??2??yn??1??yl) pyridin??2??amines

[Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39]

Iodobenzene??Catalyzed Synthesis of Imidazo [1, 2??a] pyridines from Aryl Ketones with mCPBA in Ionic Liquid

[Chang, Ya-Li; Wang, Huey-Min; Hou, Rei-Sheu; Kang, Iou-Jiun; Chen, Ling-Ching Journal of the Chinese Chemical Society, 2010 , vol. 57, # 2 p. 153 - 156]

Copper??Catalyzed Aerobic Oxidative C H Functionalization of Substituted Pyridines: Synthesis of Imidazopyridine Derivatives

[Yu, Jipan; Jin, Yunhe; Zhang, Hao; Yang, Xiaobo; Fu, Hua Chemistry - A European Journal, 2013 , vol. 19, # 49 p. 16804 - 16808]

Ring–Ring Interconversions of Nitrosoimidazoles. The Effect of some Condensed Six-Membered Rings on the Reactivity

[Billi; Cosimelli; Spinelli; Andreani; Leoni Tetrahedron, 2000 , vol. 56, # 35 p. 6527 - 6532]

More Articles...