Silica Sulfuric Acid (SSA)/Polyethylene Glycol (PEG) as a Recyclable System for the Synthesis of Quinoxalines and Pyrazines

T Huang, D Jiang, J Chen, W Gao, J Ding…

Index: Huang, Tieqiang; Jiang, Danna; Chen, Jiuxi; Gao, Wenxia; Ding, Jinchang; Wu, Huayue Synthetic Communications, 2011 , vol. 41, # 22 p. 3334 - 3343

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Citation Number: 5

Abstract

Abstract An efficient and facile method has been developed for the condensation of 1, 2- diamines with α-hydroxyketones in polyethylene glycol (PEG) to quinoxalines and pyrazines with good yields in the presence of silica sulfuric acid (SSA). The important features of the methodology are simple operations, environmentally friendliness, and no requirement for metal catalysts. Additionally, the catalyst system (SSA/PEG) could be recovered easily and ...

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