A novel ring transformation of 5-nitrouracils into 5-carbamoyluracils via the retro-michael reaction

K Hirota, Y Kitade, S Senda

Index: Hirota, Kosaku; Kitade, Yukio; Senda, Shigeo Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2409 - 2410

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Citation Number: 13

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Treatment of 1,3-disubstituted 5-nitrouracils (5) with malonamide in ethanolic sodium ethoxide caused a ring transformation to afford 1-substituted 5-carbamoyluracils (6) in good yields. ... All new compounds gave satisfactory elemental analyses and spectral properties ...