Tetrahedron

Syntheses of substituted pyridines, quinolines and diazines via palladium-catalyzed cross-coupling of aryl Grignard reagents

…, F Mongin, F Trécourt, G Quéguiner, P Knochel

Index: Bonnet, Veronique; Mongin, Florence; Trecourt, Francois; Queguiner, Guy; Knochel, Paul Tetrahedron, 2002 , vol. 58, # 22 p. 4429 - 4438

Full Text: HTML

Citation Number: 101

Abstract

The palladium-catalyzed cross-coupling reactions between arylmagnesium halides (phenylmagnesium chloride, mesitylmagnesium bromide, 4-(methoxycarbonyl) phenylmagnesium chloride and 4-cyanophenylmagnesium chloride) and halopyridines allowed the synthesis of substituted pyridines. Owing to the remarkably mild conditions used (often below 0° C), the reaction could be extended to the use of functionalized ...

Related Articles:

Microwave-assisted, efficient and regioselective Pd-catalyzed C-phenylation of halopyrimidines

[Ceide, Susana Conde; Montalban, Antonio Garrido Tetrahedron Letters, 2006 , vol. 47, # 26 p. 4415 - 4418]

Synthesis of indolylpyrimidiness via cross-coupling of indolylboronic acid with choropyrimidines: facile synthesis of meridianin D

[Heterocycles, , vol. 53, # 7 p. 1489 - 1498]

Addition and substitution reactions of chloropyrimidines with lithium reagents

[Journal of Organic Chemistry, , vol. 53, # 17 p. 4137 - 4140]

More Articles...