Tetrahedron letters

NaIO 4/KI/NaCl: a new reagent system for iodination of activated aromatics through in situ generation of iodine monochloride

L Emmanuvel, RK Shukla, A Sudalai, S Gurunath…

Index: Emmanuvel, Lourdusamy; Shukla, Ravi Kant; Sudalai, Arumugam; Gurunath, Suryavanshi; Sivaram, Swaminathan Tetrahedron Letters, 2006 , vol. 47, # 28 p. 4793 - 4796

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Citation Number: 36

Abstract

A new reagent system consisting of NaIO4/KI/NaCl in aq AcOH has been found to be effective in iodinating a variety of activated aromatic substrates via in situ-generated iodine monochloride, to furnish iodoaromatics in excellent yields. This iodination procedure has been applied successfully for a cost-effective synthesis of 3, 3′-diaminobenzidine, a key intermediate for preparing proton conducting membranes for fuel cell applications, with ...