Catalytic hydrogenation of pyridinols, quinolinols and their esters

CJ Cavallito, TH Haskell

Index: Cavallito; Haskell Journal of the American Chemical Society, 1944 , vol. 66, p. 1166,1168

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Citation Number: 29

Abstract

Summary Several alkyl and alkamine esters of 2-nitro-5-fluorobenzoic acid and 2-amino-5- fluorobenzoic acid have been prepared. All of the esters of 2-amino-5-fluoro. benzoic acid possess anesthetic properties. The toxicity of the procaine analog was slightly higher than that of procaine. All of the anesthetic esters were quite unstable and formed highly colored solutions. The compounds possess no practical value as anesthetics.