Development of a pilot scale process for the anti-Alzheimer drug (-)-galanthamine using large-scale phenolic oxidative coupling and crystallisation-induced chiral …
B Küenburg, L Czollner, J Fröhlich…
Index: Organic Process Research and Development, , vol. 3, # 6 p. 425 - 431
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Citation Number: 94
Abstract
... AG, Landeggerstrasse 7, A-2491 Neufeld, Austria, and Institute of Organic Chemistry, Vienna ... effect of variations on reaction times and reaction temperatures on process throughput. ... A consistently reproducible procedure has been developed for the crystallisation-induced chiral ...
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