Synthesis of N-urethane protected β-amino alcohols employing N-(protected-α-aminoacyl) benzotriazoles

VV Sureshbabu, NS Sudarshan…

Index: Sureshbabu, Vommina V.; Sudarshan; Muralidhar; Narendra Journal of Chemical Research, 2007 , # 12 p. 683 - 685

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Abstract

A simple and racemisation-free synthesis of N-urethane protected α-amino/peptidyl alcohols by the reduction of the corresponding easily accessible N-acylbenzotriazoles is described. The method is practical, straightforward, fast and efficient for the synthesis of amino/peptidyl alcohols. All the alcohols made were isolated in high yields and purity.

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