Synthesis and 1 H and 13 C NMR spectra of sulfur derivatives of pyrazine derived from amidation product of 2-chloropyrazine and 6-chloro-2-pyrazinecarbonitrile. …

…, K Palát, A Lyčka, Ž Odlerová

Index: Dlabal, Karel; Palat, Karel; Lycka, Antonin; Odlerova, Zelmira Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 10 p. 2493 - 2501

Full Text: HTML

Citation Number: 22

Abstract

Abstract Homolytic amidations of 2-chloropyrazine and 6-chloropyrazine-2-carbonitrile have been carried out to obtain products which have been used to prepare sulfur derivatives of pyrazine as potential tuberculostatic agents. The 1 H and 13 C NMR spectra of the products have been measured and interpreted, and the antituberculotic activity has been evaluated.

Related Articles:

In vitro antimycobacterial activity of 5-chloropyrazinamide

[Cynamon, Michael H.; Speirs, Robert J.; Welch, John T. Antimicrobial Agents and Chemotherapy, 1998 , vol. 42, # 2 p. 462 - 463]

Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation

[Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 2 p. 450 - 453]

Synthesis of 2-(d-Arabino-tetra-hydroxybutyl) pyrazine-5-sulfonic Acid

[Agricultural and Biological Chemistry, , vol. 46, # 8 p. 2169 - 2172]

Synthesis of 2-(d-Arabino-tetra-hydroxybutyl) pyrazine-5-sulfonic Acid

[Agricultural and Biological Chemistry, , vol. 46, # 8 p. 2169 - 2172]

Synthesis of 2-(d-Arabino-tetra-hydroxybutyl) pyrazine-5-sulfonic Acid

[Agricultural and Biological Chemistry, , vol. 46, # 8 p. 2169 - 2172]

More Articles...