Synthesis of nevirapine and its major metabolite
…, J Vitous, S Campbell, J Adams
Index: Grozinger; Fuchs; Hargrave; Mauldin; Vitous; Campbell; Adams Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 1 p. 259 - 263
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Citation Number: 29
Abstract
Abstract Several synthetic methods were developed during the process optimization for the large scale synthesis of nevirapine (1), a non-nucleoside inhibitor of HIV-1 Reverse Transcriptase. The synthesis of its putative major metabolite 11-cyclopropyl-5, 11-dihydro- ...
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