Aniline alkylation with di-and tribromopropane

VM Ismailov, IA Mamedov, NN Yusubov

Index: Ismailov; Mamedov; Yusubov Russian Journal of Organic Chemistry, 2009 , vol. 45, # 8 p. 1250 - 1251

Full Text: HTML

Citation Number: 0

Abstract

At excess K2CO3 in DMSO environment the condensation of aniline (I) with 1, 3- dibromopropane (II) at heating (60–80 C) led to the formation of N-(3-bromopropyl)-aniline (III) and N-phenylazetidine (IV). At higher temperature the fraction of the cyclic product increased.

Related Articles:

N-Heterocyclization of primary amines with dihalides using microreactors

[He, Hongjie; Lin, Qi; Liu, Xiaofeng; Yang, Yongtai; Zhou, Yaming; Jia, Yu; Gao, Xiang Synthetic Communications, 2012 , vol. 42, # 17 p. 2512 - 2525]

4, 4′-Di-tert-butylbiphenyl-catalysed reductive opening of azetidines with lithium: A direct preparation of 3, N-dilithioalkylamines

[Almena, Juan; Foubelo, Francisco; Yus, Miguel Tetrahedron, 1994 , vol. 50, # 19 p. 5775 - 5782]

Microwave-assisted synthesis of azetidines in aqueous media

[Burkett, Brendan A.; Ting, Samuel Z.; Gan, Gwendolyn C. S.; Chai, Christina L. L. Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6590 - 6592]

4, 4′-Di-tert-butylbiphenyl-catalysed reductive opening of azetidines with lithium: A direct preparation of 3, N-dilithioalkylamines

[Almena, Juan; Foubelo, Francisco; Yus, Miguel Tetrahedron, 1994 , vol. 50, # 19 p. 5775 - 5782]

More Articles...