Reaction of 1-methylthio-3, 4-dihydroisoquinolines with amines

YV Shklyaev, VA Glushkov, NB Belogub…

Index: Shklyaev; Glushkov; Belogub; Misyura Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 6 p. 689 - 695

Full Text: HTML

Citation Number: 1

Abstract

Abstract A study was carried out on the reaction of 1-methylthio-3, 4-dihydroisoquinolines with aromatic and aliphatic amines, thiourea, semicarbazide, and thiosemicarbazide. The reactions with anthranilic acid and 2-amino-3-carboethoxy-4, 5-dmeurylthiophene give 6, 6- dmethyl-5, 6-dihydro-8H-isoquino [1, 2-blquinazolin-8-one and 6, 6, 9, 10-tetramethyl-5, 6- dihydro-8H-benzo [i] thieno [2, 3-b] quinolizin-8-one, respectively. 1-Semicarbazido-and 1 ...