Tetrahedron letters

Reductive N-alkylation of aromatic amines and nitro compounds with nitriles using polymethylhydrosiloxane

CR Reddy, K Vijeender, PB Bhusan, PP Madhavi…

Index: Reddy, Ch. Raji; Vijeender; Bhusan, P. Bibhuti; Madhavi, P. Phani; Chandrasekhar Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2765 - 2768

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Citation Number: 23

Abstract

The potential utility of polymethylhydrosiloxane (PMHS) as a reducing agent for reductive N- alkylation of aromatic amines and nitro compounds using nitriles as an alkylating agent and Pd (OH) 2/C as a catalyst is described. The application of this method for the synthesis of several heterocyclic compounds is also reported.

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