Preparation of 7??aminoquinolines as candidate antiparasitic agents

A Markovac, GS Wu, MP Lamontagne…

Index: Markovac; Wu; LaMontagne; et al. Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 4 p. 829 - 832

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Abstract

Abstract A series of ten 7-quinolinediamines were prepared and evaluated for potential antiparasitic activity against P. berghei, P. cynomolgi, L. donovani and T. rhodesiense. Compounds 1d and 8 showed activity being slightly effective against L. donovani in hamsters.