Helvetica Chimica Acta

Unexpected Approach to the Synthesis of 2??Phenylquinoxalines and Pyrido [2, 3??b] pyrazines via a Regioselective Reaction

A Alizadeh, J Mokhtari

Index: Alizadeh, Abdolali; Mokhtari, Javad Helvetica Chimica Acta, 2013 , vol. 96, # 1 p. 124 - 129

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Citation Number: 2

Abstract

Abstract An unexpected approach to the preparation of quinoxaline and pyrido [2, 3-b] pyrazine derivatives 5 is described. The reaction between 1H-indole-2, 3-diones 1, 1-phenyl- 2-(triphenylphosphoranylidene) ethanone (2), and benzene-1, 2-or pyridine-2, 3-diamines 3 proceeds in MeOH under reflux in good to excellent yields (Scheme 1 and Table). No co- catalyst or activator is required for this multi-component reaction (MCR), and the reaction ...

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