Chemoenzymatic synthesis of 7-Deaza cyclic adenosine 5'-diphosphate ribose analogues, membrane-permeant modulators of intracellular calcium release

B Zhang, VC Bailey, BVL Potter

Index: Graham, Steven M.; Macaya, Daniel J.; Sengupta, Raghuvir N.; Turner, Kevin B. Organic Letters, 2004 , vol. 6, # 2 p. 233 - 236

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Citation Number: 15

Abstract

... J. Org. ... 8-Bromo-7-deazaadenosine is proposed to adopt a syn conformation as shown in (b). ... compound 15 as the initial building block, which could in principle conveniently be reacted with a range of nucleophilic amines to introduce a variety of N-6-substituted adenosine ...