Tetrahedron

Synthesis, structure and the binding properties of the amide-based anion receptors derived from 1H-indole-7-amine

T Zieliński, P Dydio, J Jurczak

Index: Zielinski, Tomasz; Dydio, Pawel; Jurczak, Janusz Tetrahedron, 2008 , vol. 64, # 3 p. 568 - 574

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Citation Number: 41

Abstract

Indole-7-amine was investigated as an alternative to aniline in construction of amide-based anion receptors. Replacement of aniline with indolamine introduces additional binding site— indolyl NH, which can enhance anion binding for more than five times. The molecular modelling of indole-containing receptors revealed the correlation between their conformational preferences and their affinity towards anions.