Tetrahedron

Easy α-alkylation of ketones with alcohols through a hydrogen autotransfer process catalyzed by RuCl 2 (DMSO) 4

R Martínez, DJ Ramón, M Yus

Index: Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel Tetrahedron, 2006 , vol. 62, # 38 p. 8988 - 9001

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Citation Number: 148

Abstract

The electrophilic α-alkylation of ketones with alcohols is accomplished by a hydrogen autotransfer process catalyzed by RuCl2 (DMSO) 4. The reaction can produce either simple alkylated ketones or α, β-unsaturated ketones just by choosing the appropriate starting ketones (methyl ketones or bicyclic methylenic ketones, respectively), as well as quinolines (by using 2-aminobenzyl alcohol derivatives) or the corresponding alcohol derivatives by ...

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