Science

Amine (imine) diphosphine iron catalysts for asymmetric transfer hydrogenation of ketones and imines

W Zuo, AJ Lough, YF Li, RH Morris

Index: Zuo, Weiwei; Lough, Alan J.; Li, Young Feng; Morris, Robert H. Science, 2013 , vol. 342, # 6162 p. 1080 - 1083

Full Text: HTML

Citation Number: 153

Abstract

Abstract A rational approach is needed to design hydrogenation catalysts that make use of Earth-abundant elements to replace the rare elements such as ruthenium, rhodium, and palladium that are traditionally used. Here, we validate a prior mechanistic hypothesis that partially saturated amine (imine) diphosphine ligands (P-NH-NP) activate iron to catalyze the asymmetric reduction of the polar bonds of ketones and imines to valuable ...

Related Articles:

Rate enhancement of lipase-catalyzed reaction in supercritical carbon dioxide

[Matsuda, Tomoko; Tsuji, Kazuhiko; Kamitanaka, Takashi; Harada, Tadao; Nakamura, Kaoru; Ikariya, Takao Chemistry Letters, 2005 , vol. 34, # 8 p. 1102 - 1103]

Efficient syntheses of fluorinated aryl alcohols of high enantiomeric purity via boronic esters

[Singh; Twamley; Fabry-Asztalos; Matteson; Shreeve Journal of Organic Chemistry, 2000 , vol. 65, # 23 p. 8123 - 8125]

Efficient Synthesis of (1R)??[3, 5??Bis (trifluoromethyl) phenyl] Ethanol, a Key Intermediate for Aprepitant, an NK??1 Receptor Antagonist

[Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T. Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446]

Efficient Synthesis of (1R)??[3, 5??Bis (trifluoromethyl) phenyl] Ethanol, a Key Intermediate for Aprepitant, an NK??1 Receptor Antagonist

[Vankawala, Pravinchandra J.; Kolla, Naveenkumar; Elati, Chandrashekar R.; Sreenivasulu; Kumar, K. Arun; Anjaneyulu, Yerrimilli; Venkatraman, Sundaram; Bhattacharya, Apurba; Mathad, Vijayavitthal T. Synthetic Communications, 2007 , vol. 37, # 19 p. 3439 - 3446]

More Articles...