Pharmaceutical Chemistry Journal

Method of preparation of pyrrolo [3, 2-d] pyrimidine (9-desazapurine) and its 4-oxo-3, 4-dihydro derivative (9-desazahypoxanthine)

LV Éktova, MN Preobrazhenskaya

Index: Ektova, L. V.; Preobrazhenskaya, M. N. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 7 p. 572 - 574 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 7 p. 860 - 863

Full Text: HTML

Citation Number: 0

Abstract

One of the relatively readily available starting compounds for the preparation of substituted pyrrolo [3, 2-d] pyrimidines is 4-oxo-3, 4-dihydro-7-formylpyrrolo [3, 2-d] pyrimidine (I), which was obtained by reacting a Vilsmeier reagent with 4-oxo-5-amino-6-methyl-3, 4-

Related Articles:

Development of a practical synthesis of a purine nucleoside phosphorylase inhibitor: BCX-4208

[Kamath, Vivekanand P.; Juarez-Brambila, Jesus J.; Morris, Christopher B.; Winslow, Christopher D.; Morris Jr., Philip E. Organic Process Research and Development, 2009 , vol. 13, # 5 p. 928 - 932]

Pyrrolo [3, 2-d] pyrimidines. IV. Synthesis and antibacterial and antitumor activity of 2, 4, 7-substituted pyrrolo [3, 2-d] pyrimidines

[Sizova, O. S.; Britikova, N. E.; Novitskii, K. Yu.; Shcherbakova, L. I.; Pershin, G. N.; et al. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 11 p. 834 - 838 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 11 p. 1338 - 1343]

Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors.

[Shih, Hsiencheng; Cottam, Howard Brinkerhoff; Carson, Dennis Anthony Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 3 p. 364 - 367]

Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors.

[Chemical and pharmaceutical bulletin, , vol. 50, # 3 p. 364 - 367]

Pyrrolo [3, 2-d] pyrimidines. IV. Synthesis and antibacterial and antitumor activity of 2, 4, 7-substituted pyrrolo [3, 2-d] pyrimidines

[Pharmaceutical Chemistry Journal, , vol. 16, # 11 p. 834 - 838 Khimiko-Farmatsevticheskii Zhurnal, , vol. 16, # 11 p. 1338 - 1343]

More Articles...