Synthesis of 3-Alkoxy-4-hydroxyphenylacetic Acids from Methyl 3-Alkoxybenzoates

YS Jung, TS Kang, JC Lee, CM Seong…

Index: Jung; Kang; Lee; Seong; Ham; Park Synthetic Communications, 2001 , vol. 31, # 3 p. 455 - 462

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Citation Number: 2

Abstract

Vanilloids are natural irritants possessing a 4-hydroxy-3-methoxybenzyl group as essential moiety to express their bioactivity 1-3 View all references. Besides their irritancy, vanilloids have attracted considerable attention for the last decade due to their strong analgesic properties 4-5 View all references. Capsaicin and its ultrapotent analog, resiniferatoxin (RTX), are the best-known natural vanilloids. In the course of our research aimed at the development of new vanilloids as ...