Exploiting tautomerism for switching and signaling

…, S Simeonov, V Kurteva, D Nedeltcheva…

Index: Antonov, Liudmil; Deneva, Vera; Simeonov, Svilen; Kurteva, Vanya; Nedeltcheva, Daniela; Wirz, Jakob Angewandte Chemie - International Edition, 2009 , vol. 48, # 42 p. 7875 - 7878

Full Text: HTML

Citation Number: 40

Abstract

Herein, we demonstrate a conceptual idea for a tautomeric switch based on implementation of a flexible piperidine unit in 4-(phenyldiazenyl) naphthalen-1-ol. The results show that a directed shift in the position of the tautomeric equilibrium can be achieved through protonation/deprotonation in a number of solvents. The developed molecular switch, in spite of the simple host–guest system, has shown acceptable complexation ability towards ...

Related Articles:

Synthesis and cholinesterase activity of phenylcarbamates related to Rivastigmine, a therapeutic agent for Alzheimer's disease

[Mustazza, Carlo; Borioni, Anna; Giudice, Maria Rosaria Del; Gatta, Franco; Ferretti, Rosella; Meneguz, Annarita; Volpe, Maria Teresa; Lorenzini, Paola European Journal of Medicinal Chemistry, 2002 , vol. 37, # 2 p. 91 - 109]

Anionic ortho-Fries Rearrangement, a Facile Route to Arenol-Based Mannich Bases

[Assimomytis, Nikos; Sariyannis, Yiannis; Stavropoulos, Georgios; Tsoungas, Petros G.; Varvounis, George; Cordopatis, Paul Synlett, 2009 , # 17 p. 2777 - 2782]

The activation of aminals and aminol ethers by sulfur dioxide and their reactions with electron rich aromatic compounds

[Heaney, Harry; Papageorgiou, George; Wilkins, Robert F. Tetrahedron, 1997 , vol. 53, # 39 p. 13361 - 13372]

Alkylation of amino acids and glutathione in water by o-quinone methide. Reactivity and selectivity

[Modica; Zanaletti; Freccero; Mella Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 41 - 52]

The activation of aminals and aminol ethers by sulfur dioxide and their reactions with electron rich aromatic compounds

[Heaney, Harry; Papageorgiou, George; Wilkins, Robert F. Tetrahedron, 1997 , vol. 53, # 39 p. 13361 - 13372]

More Articles...