Modified coumarins. 4. synthesis and biological properties of cyclopentaneannelated furocoumarins

…, YL Garazd, SV Shilin, TN Panteleimonova…

Index: Garazd; Shilin; Panteleimonova; Khilya Chemistry of Natural Compounds, 2002 , vol. 38, # 3 p. 230 - 242

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Citation Number: 5

Abstract

Abstract Psoralen and allopsoralen analogs that contain an annelated cyclopentane were synthesized from 7-hydroxyand 9-hydroxy-1, 2, 3, 4-tetrahydrocyclopenta [c] chromen-4- ones. 9-Phenyl-1, 2, 3, 4-tetrahydrocyclopenta [c] furo [3, 2-g] chromen-4-one exhibited low toxicity, acted as a CNS stimulant, and exhibited cardiotropic activity.