Tetrahedron

Chiral heterocyclic β-enamino esters: convenient synthesis and diastereoselective reduction

…, C Vanucci-Bacqué, MC Fargeau-Bellassoued…

Index: Calvet, Sandrine; David, Olivier; Vanucci-Bacque, Corinne; Fargeau-Bellassoued, Marie-Claude; Lhommet, Gerard Tetrahedron, 2003 , vol. 59, # 33 p. 6333 - 6339

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Citation Number: 35

Abstract

During the course of our research toward the preparation of chiral polyfunctional heterocycles as precursors of natural products, we are interested in developing new methods able to spare sacrificial chiral auxiliaries by their introduction in a late stage of the synthesis. In a recent publication, 1 we described a convenient preparation of chiral pyrrolidine and piperidine β-enamino esters whose reduction products often constitute valuable intermediates in the synthesis ...

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