An efficient method for the synthesis of acylals from aldehydes using silica-supported perchloric acid (HClO 4–SiO 2)

…, VS Jamode, NS Joshi, AV Biradar, RY Deshmukh

Index: Kamble, Vinod T.; Jamode, Vasant S.; Joshi, Neeta S.; Biradar, Ankush V.; Deshmukh, Rameshchandra Y. Tetrahedron Letters, 2006 , vol. 47, # 31 p. 5573 - 5576

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Citation Number: 65

Abstract

The synthesis of acylals from structurally diverse aldehydes has been performed in excellent yields under solvent-free conditions using HClO4–SiO2 as a mild, convenient, reusable, and heterogeneous catalyst. The procedure is operationally simple, environmentally benign and has the advantage of enhanced atom utilization. Furthermore, the catalyst can be recovered simply and reused efficiently a number of times without appreciable loss of activity.