J. Chem. Soc., Perkin Trans. 1

Novel asymmetric phenylselenium-induced lactamizations of olefinic amides: stereoselective routes to α-and β-amino acids

SK Chung, TH Jeong, DH Kang

Index: Chung, Sung-Kee; Jeong, Tae-Heum; Kang, Dong-Ho Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 5 p. 969 - 976

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Abstract

Organoselenium-induced cyclofunctionalization of the ()--(α, β-unsaturated) acylprolinamides 1, 7 and 14 has been found to produce the 7-membered bislactam products 2 and 15, or the 6-membered phenylselenolactam products 8 and 9 depending on the substitution pattern of the enone moiety of the starting material. The