An efficient synthesis of 2H-chromen-3-yl derivatives via CuI/(NH 4) 2 HPO 4 catalyzed reaction of O-propargyl salicylaldehydes with active methylene compounds

K Kumari, DS Raghuvanshi, KN Singh

Index: Kumari, Kumkum; Raghuvanshi, Dushyant Singh; Singh, Krishna Nand Tetrahedron, 2013 , vol. 69, # 1 p. 82 - 88

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Citation Number: 14

Abstract

2H-Chromen-3-yl-methylenemalononitriles/cyanoacrylates/cyanoacrylamides with variant structural features have been serendipitously formed during an endeavour to prepare 5H- chromeno [3, 4-c] pyridine using CuI/(NH4) 2HPO4 catalyzed reaction of O-propargyl salicylaldehyde with malononitrile/ethyl cyanoacetate/cyanoacrylamide. The process is convenient, speedy and high yielding, and the products formed have been finally ...