Development of 4-aminoquinoline-1, 3, 5-triazine conjugates as potent antibacterial agent through facile synthetic route

HR Bhat, PK Pandey, SK Ghosh, UP Singh

Index: Bhat, Hans Raj; Pandey, Pankaj Kumar; Ghosh, Surajit Kumar; Singh, Udaya Pratap Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 5056 - 5065

Full Text: HTML

Citation Number: 8

Abstract

Abstract A series of novel hybrid 4-aminoquinoline-1, 3, 5-triazine derivatives were developed and subsequently tested against representative Gram-positive and Gram- negative microorganisms for determination of their antibacterial activity. Screening results indicate that, title molecule exhibit moderate to potent activity in comparison to standard. These hybrid derivatives were synthesized through a facile synthetic routes and structure ...

Related Articles:

Novel route to the synthesis of 4-quinolyl isothiocyanates

[Zhong, Boyu; Al-Awar, Rima S.; Shih, Chuan; Grimes Jr., John H.; Vieth, Michal; Hamdouchi, Chafiq Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2161 - 2164]

Discovering some novel 7-chloroquinolines carrying a biologically active benzenesulfonamide moiety as a new class of anticancer agents

[Al-Dosari, Mohammed Salem; Ghorab, Mostafa Mohamed; Al-Said, Mansour Sulaiman; Nissan, Yassin Mohammed Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 1 p. 50 - 58]

More Articles...