Tetrahedron Letters

Laccase-generated quinones in naphthoquinone synthesis via Diels–Alder reaction

S Witayakran, A Zettili, AJ Ragauskas

Index: Witayakran, Suteera; Zettili, Abdullah; Ragauskas, Arthur J. Tetrahedron Letters, 2007 , vol. 48, # 17 p. 2983 - 2987

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Citation Number: 42

Abstract

The tandem synthesis of naphthoquinones was conducted from the reaction of laccase- generated quinones and acyclic dienes via Diels–Alder reaction. This reaction was carried out under mild condition in aqueous medium and yielded naphthoquinones up to 80%. In addition, the effect of solvent was also investigated and water was shown to be optimal for this reaction.

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