Synthesis

Phenazines and natural products; novel synthesis of saphenic acid

L Petersen, KJ Jensen, J Nielsen

Index: Petersen, Lars; Jensen, Knud J.; Nielsen, John Synthesis, 1999 , # 10 p. 1763 - 1766

Full Text: HTML

Citation Number: 7

Abstract

Abstract: The natural product saphenic acid (6-(1-hydroxyethyl)-1-phenazinecarboxylic acid) was synthesized from readily accessible starting materials. The desired product was obtained in an overall yield of 22% for four steps with the key steps being formation of a diphenylamine, followed by cyclization under alkaline and reducing conditions. Assignments of 1H NMR spectra were achieved by homo-and heteronuclear 1D and 2D correlations. ...

Related Articles:

Quinolone antibacterials. 1. 7??(2??substituted??4??thiazolyl and thiazolidinyl) quinolones

[Zhang; Haemers; Vanden Berghe; Pattyn; Bollaert; Levshin Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 3 p. 673 - 683]

Quinolone antibacterials. 1. 7??(2??substituted??4??thiazolyl and thiazolidinyl) quinolones

[Zhang; Haemers; Vanden Berghe; Pattyn; Bollaert; Levshin Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 3 p. 673 - 683]

Quinolone antibacterials. 1. 7??(2??substituted??4??thiazolyl and thiazolidinyl) quinolones

[Zhang; Haemers; Vanden Berghe; Pattyn; Bollaert; Levshin Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 3 p. 673 - 683]

More Articles...