Dinucleotides containing two allyl groups by combinations of allyl phosphotriesters, 5-allyl-, 2′-O-allyl-and 2′-arabino-O-allyl uridine derivatives as substrates for …

P Børsting, M Freitag, P Nielsen

Index: Borsting, Philip; Freitag, Morten; Nielsen, Poul Tetrahedron, 2004 , vol. 60, # 48 p. 10955 - 10966

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Citation Number: 23

Abstract

Five different dinucleotides, each containing two allyl groups in various positions, were prepared and studied as substrates for ring-closing metathesis reactions. These dinucleotides were designed from appropriate nucleoside building blocks combining four different positions for the allyl group; the allyl phosphotriester linkage, 5-allyl-2′- deoxyuridine, and ribo-as well as arabino-configured 2′-O-allyluridine. Thus, convenient ...