Water solubility, antioxidant activity and cytochrome C binding of four families of exohedral adducts of C 60 and C 70

P Witte, F Beuerle, U Hartnagel, R Lebovitz…

Index: Witte, Patrick; Beuerle, Florian; Hartnagel, Uwe; Lebovitz, Russell; Savouchkina, Anastasia; Sali, Sevda; Guldi, Dirk; Chronakis, Nikos; Hirsch, Andreas Organic and Biomolecular Chemistry, 2007 , vol. 5, # 22 p. 3599 - 3613

Full Text: HTML

Citation Number: 49

Abstract

Over the past decade, surface-modified, water soluble fullerenes have been shown by many different investigators to exhibit strong antioxidant activity against reactive oxygen species (ROS) in vitro and to protect cells and tissues from oxidative injury and cell deathin vivo. Nevertheless, progress in developing fullerenes as bona fide drug candidates has been hampered by three development issues: 1) lack of methods for scalable synthesis; 2) ...

Related Articles:

Organopalladium approaches to prostaglandins. 3. Synthesis of bicyclic and tricyclic 7-oxaprostaglandin endoperoxide analogs via oxypalladation of norbornadiene

[Larock, Richard C.; Leach, Douglas R. Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2144 - 2148]

Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies

[Hum, Gabriel; Wooler, Krista; Lee, Jeremy; Taylor, Scott D. Canadian Journal of Chemistry, 2000 , vol. 78, # 5 p. 642 - 655]

Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies

[Hum, Gabriel; Wooler, Krista; Lee, Jeremy; Taylor, Scott D. Canadian Journal of Chemistry, 2000 , vol. 78, # 5 p. 642 - 655]

Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies

[Hum, Gabriel; Wooler, Krista; Lee, Jeremy; Taylor, Scott D. Canadian Journal of Chemistry, 2000 , vol. 78, # 5 p. 642 - 655]

Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies

[Hum, Gabriel; Wooler, Krista; Lee, Jeremy; Taylor, Scott D. Canadian Journal of Chemistry, 2000 , vol. 78, # 5 p. 642 - 655]

More Articles...