Tetrahedron letters

Facile synthesis of α-trifluoromethylated alcohols from trifluoroacetaldehyde ethyl hemiacetal

T Kubota, M Iijima, T Tanaka

Index: Kubota, Toshio; Iijima, Masahiro; Tanaka, Tatsuo Tetrahedron Letters, 1992 , vol. 33, # 10 p. 1351 - 1354

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Citation Number: 40

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Trifluoroacetaldehyde ethyl hemiacetal reacted with nucleophilic organosilanes such as cyanotrimethylsilane, allyltrimethylsilane, or enol trimethylsilyl ethers in the presence of Lewis acid to afford a series of α-trifluoromethylated alcohols in high yield.

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