Investigation of the Mechanism of Action of Pyrogallol–Phloroglucinol Transhydroxylase by Using Putative Intermediates

…, U Bartlewski??Hof, J Rétey

Index: Paizs, Csaba; Bartlewski-Hof, Ulrike; Retey, Janos Chemistry - A European Journal, 2007 , vol. 13, # 10 p. 2805 - 2811

Full Text: HTML

Citation Number: 10

Abstract

Abstract Pyrogallol–phloroglucinol transhydroxylase from Pelobacter acidigallici, a molybdopterin-containing enzyme, catalyzes a key reaction in the anaerobic degradation of aromatic compounds. In vitro, the enzymatic reaction requires 1, 2, 3, 5-tetrahydroxybenzene as a cocatalyst and the transhydroxylation occurs without exchange with hydroxy groups from water. To test our previous proposal that the transfer of the hydroxy group occurs via ...

Related Articles:

Stereoselective synthesis of an analog of podophyllotoxin by an intramolecular Diels-Alder reaction

[Jung, Michael E.; Lam, Patrick Yuk-Sun; Mansuri, Muzzamil M.; Speltz, Laurine M. Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1087 - 1105]

The invention of radical reactions: Part XVI. Radical decarboxylative bromination and iodination of aromatic acids

[Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z. Tetrahedron, 1987 , vol. 43, # 19 p. 4321 - 4328]

Stereoselective synthesis of an analog of podophyllotoxin by an intramolecular Diels-Alder reaction

[Jung, Michael E.; Lam, Patrick Yuk-Sun; Mansuri, Muzzamil M.; Speltz, Laurine M. Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1087 - 1105]

Radical decarboxylative bromination of aromatic acids

[Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z. Tetrahedron Letters, 1985 , vol. 26, # 48 p. 5939 - 5942]

More Articles...