An efficient method for sterically demanding Suzuki–Miyaura coupling reactions

Q Zhao, C Li, CH Senanayake…

Index: Zhao, Qing; Li, Chengxi; Senanayake, Chris H.; Tang, Wenjun Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2261 - 2265

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Citation Number: 35

Abstract

Sterically hindered biaryl structures exist in many biologically important natural products,[1] and they also serve as pivotal frameworks for efficient ligands in homogenous catalysis.[2] Their syntheses have attracted a great deal of interest. The palladium-catalyzed Suzuki– Miyaura cross-coupling reaction [3–5] to construct biaryl compounds is particularly attractive owing to its versatility and compatibility with various functional groups. However, the ...

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