Steroid dimer formation: metal reduction of Methyl Androst-4-ene-3, 17-dion-19-oate

JF Templeton, H Majgier-Baranowska, K Marat

Index: Templeton, John F.; Majgier-Baranowska, Helena; Marat, Kirk Steroids, 2000 , vol. 65, # 4 p. 219 - 223

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Citation Number: 8

Abstract

Two isomeric dimeric steroids, 3, 3′-bis (methyl 3-hydroxyandrost-4-en-17-on-19-oate-3- yl), with symmetrical (α, α′) and unsymmetrical structures (α, β′), have been obtained by reduction of methyl androst-4-ene-3, 17-dion-19-oate with zinc in aqueous acetic acid together with the major products, the isomeric methyl 5α-and 5β-androst-3-en-17-on-19- oates. The structures of the dimers and unsaturated products are supported by ...