Novel synthesis modes and properties of [1, 4] benzodioxinopyridazines

JP Chupp, CR Jones, ML Dahl

Index: Chupp, John P.; Jones, Claude R.; Dahl, Maria L. Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 3 p. 789 - 798

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Citation Number: 4

Abstract

Abstract A simple synthesis involving fusion of catechol and derivatives with 3, 4, 5- trichloropyridazine has furnished 4-chloro [1, 4] benzodioxino [2, 3-c] pyridazines 5 for the first time. This new method complements the previously reported base promoted procedure for preparing 4-chloro [1, 4] benzodioxino-[2, 3-d] pyridazines 3. Employing both methods, 4- (trifluoromethyl) catechol was converted to the four regio isomers 3b, c and 5c, d. Structure ...