Tetrahedron

α-Chloro-enamines—III: Substitution and elimination reactions on α-chloroenamine-β-acid derivatives—the synthesis of an ynamine amide and an ynamine ester

R Buyle, HG Viehe

Index: Buyle,R.; Viehe,H.G. Tetrahedron, 1969 , vol. 25, p. 3447 - 3451

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Citation Number: 6

Abstract

Readily accessible β-chloroacyl-α-chloroenamines have two reactive Cl atoms which can be substituted successively with nucleophilic reagents. An ynamine amide and an ynamine ester have been prepared from N, N-diethylchloroacetamide via its β-chloro-β-chloroacyl-β- chloroenamine by chlorine elimination with lithium amalgam.

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