Ceric Ammonium Nitrate: An efficient catalyst for one-pot synthesis of 2, 2, 4-Trimethyl-1, 2-dihydroquinolines

S Durgadas, VK Chatare, K Mukkanti…

Index: Durgadas, Shylaprasad; Chatare, Vijay K.; Mukkanti, Khagga; Pal, Sarbani Letters in Organic Chemistry, 2010 , vol. 7, # 4 p. 306 - 310

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Citation Number: 9

Abstract

Ceric ammonium nitrate (CAN) catalyzed the one-pot synthesis of 2, 2, 4-trimethyl-1, 2- dihydroquinoline derivatives from substituted anilines and acetone via a modified Skraup reaction. The methodology was used to synthesize a novel dihydroquinoline-based compound derived from an anti-inflammatory agent nimesulide.

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