Molecules

Easy access to a cyclic key intermediate for the synthesis of trisporic acids and related compounds

JA González-Delgado, G Escobar, JF Arteaga…

Index: Gonzalez-Delgado, Jose A.; Escobar, Gustavo; Arteaga, Jesus F.; Barrero, Alejandro F. Molecules, 2014 , vol. 19, # 2 p. 1748 - 1762

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Citation Number: 4

Abstract

Abstract: The synthesis of a cyclohexane skeleton possessing different oxygenated functional groups at C–3, C–8 and C–9, and a Δ 1, 6-double bond has been accomplished in 10 steps with an overall 17% yield. This compound is a key intermediate for access to a wide range of compounds of the bioactive trisporoid family. The synthetic sequence consists of the preparation of a properly functionalized epoxygeraniol derivative, and its ...

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