Debottlenecking the synthesis route of asenapine

M Linden, T Roeters, R Harting…

Index: Organic Process Research and Development, , vol. 12, # 2 p. 196 - 201

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Citation Number: 9

Abstract

... Organic Process Research & Development. ... controlled. The reversed addition process evolved into a procedure in which part of the magnesium turnings (ie, approximately 0.6 equiv) was first suspended in toluene. The ...