Syntheses of aromatic substituted hydrazino-thiazole derivatives to clarify structural characterization and antioxidant activity between 3-arylsydnonyl and aryl …

MH Shih, YS Su, CL Wu

Index: Shih, Mei-Hsiu; Su, Yu-Sheng; Wu, Cheng-Ling Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 8 p. 1126 - 1135

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Citation Number: 39

Abstract

This work clarifies the structural characterization and antioxidant activity between aromatic and 3-arylsydnonyl substituted hydrazino-thiazoles by further synthesizing a series of aromatic ring-substituted hydrazino-thiazole derivatives 8a—h and 9a—h. Hydrazino- thiazole derivatives 8a—h and 9a—h were obtained by reacting aromatic or heterocyclic aromatic aldehyde thiosemicarbazones 7a—h with cyclization reagents ethyl 2- ...