New Strategy for the Stereocontrolled Construction of Decalins and Fused Polycycles via a Tandem Diels-Alder Ring-Opening Sequence

M Lautens, E Fillion

Index: Lautens, Mark; Fillion, Eric Journal of Organic Chemistry, 1996 , vol. 61, # 23 p. 7994 - 7995

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Citation Number: 33

Abstract

Tandem DielsrAlder cycloadditions efficiently construct multiple carbonrcarbon bonds while generating complex polycyclic structures in a single chemical step. 1 For example, the “pincer” DielsrAlder served as a cornerstone in Paquette's classic synthesis of dodecahedrane. 2 However, the synthetic utility of the “pincer” DielsrAlder reaction remains underutilized in organic synthesis. We considered that the “pincer” cycloaddition with ...