Journal of the American Chemical Society

Polyphosphoric Acid as a Reagent in Organic Chemistry. VI. 1 The Hydrolysis of Nitriles to Amides

HR Snyder, CT Elston

Index: Snyder; Elston Journal of the American Chemical Society, 1954 , vol. 76, p. 3039

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Citation Number: 51

Abstract

Polyphosphoric Acid as a Reagent in Organic Chemistry. V. Conversion of Acids to Substituted Amides ; Further Observations on the Lossen Reaction BY H. R. SNYDEU AND CLAYTON T ELSTON' RECEIVED JANUARY 21, 1954 In an earlier paper2 it was postulated that the re- action of hydroxylamine with aromatic carboxylic acids in the presence of polyphosphoric acid pro- ceeds to the amine by way of an intermediate hy- droxamic acid. In agreement with this ...