Synthesis of 3, 5-disubstituted 1, 2, 4-triazole derivatives-An alternative preparation of the C-analogue of ribavirin

T Vaněk, J Farkaš, J Gut

Index: Vanek,T. et al. Collection of Czechoslovak Chemical Communications, 1979 , vol. 44, p. 1334 - 1338

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Citation Number: 10

Abstract

Abstract Condensation of ethyl acetothioimidate hydrochloride (III) with amidrazones IV afforded 3-methyl-5-phenyl-1, 2, 4-triazole (Va) and ethyl 3-methyl-1, 2, 4-triazole-5- carboxylate (Vb). Analogously, the thioimidate hydrochloride VI was transformed into ethyl ...